Purpose
Starna’s dissolution flow cells are engineered for continuous operation.
They combine fully fused quartz flow paths, precision-machined enclosures, and optimised internal geometries to ensure smooth laminar flow, minimise bubble retention, and provide reliable sealing. This ensures consistent, traceable performance in pharmaceutical dissolution testing.
Description and Discussion
Engineered for Reliability. Proven in Regulated Laboratories
Purpose‑built dissolution flow cells are designed for continuous, contamination‑free operation in regulated analytical environments and feature a metal‑jacketed construction for added durability.
Each flow cell features a fully fused quartz sample chamber, manufactured by direct heat fusion without adhesives. The quartz cell body is precision-mounted within a machined metal jacket, providing mechanical strength, dimensional stability, and secure integration with screw-in fittings.
All cells are pressure-tested to 5 bar after final assembly, laser-engraved with a unique serial number and verified pathlength and verified for traceability and consistent performance across batches.
For short pathlengths of 2 mm or less, sub-micron pathlength accuracy (±0.2 µm) is verified by interference spectrometry, providing confidence in both routine QC and advanced R&D applications.
Engineered inlet and outlet geometry promotes smooth, laminar flow and reduces bubble retention, supporting high-throughput dissolution testing and continuous, automated drug release analysis.
A wide range of aperture geometries, including long, wide, medium, micro and sub‑micro, supports multiple dissolution protocols, minimises sample loss and delivers consistent, reproducible results.
Suitable for research, development, and routine analytical testing, Starna Dissolution Flow Cells deliver reliable, traceable optical measurements.
| Feature | Specification / Detail |
|
Construction |
Quartz body: direct heat‑fusion construction, contained in a metal enclosure. |
|
Pressure Testing |
Pressure tested to 5 bar |
|
Traceability |
Laser-engraved path length and serial number |
|
Path Length Accuracy |
Path lengths of ≤ 2mm are measured interferometrically to ± 0.2 µm. Please refer to the published specification for path lengths of 5 mm and above. |
|
Flow Profile |
Continuous, laminar; engineered to reduce bubbles |
|
Connection Types |
M6, Luer Lock, Gripper fittings |
|
Configuration Options |
Long Aperture (584.4) |
|
Pharmacopeial Compliance |
USP, Ph. Eur., JP |
|
System Compatibility |
Designed for full integration with automated high-throughput systems |
|
Applications |
Real-time drug release, IVIVC studies, R&D, QC, and automated workflows |
Catalogue Number
|
Type |
Material |
Pathlength |
Z height |
Nominal volume |
|
583.4 |
Q |
5 |
8.5, 15, 20 |
0.225 |
|
583.4 |
Q |
10 |
8.5, 15, 20 |
0.450 |
|
583.4 |
Q |
20 |
8.5, 15, 20 |
0.900 |
|
583.4 |
Q |
40 |
8.5, 15, 20 |
1.800 |
|
583.4 |
Q |
50 |
8.5, 15, 20 |
2.250 |
|
583.4 |
Q |
100 |
8.5, 15, 20 |
4.500 |
|
583.4.14 |
Q |
1 |
15, 20 |
0.056 |
|
583.4.14 |
Q |
2 |
15, 20 |
0.112 |
|
583.4.14 |
Q |
5 |
15, 20 |
0.280 |
|
583.4.14 |
Q |
10 |
15, 20 |
0.560 |
|
583.65 |
Q |
0.1 |
15, 20 |
0.029 |
|
583.65 |
Q |
0.2 |
15, 20 |
0.036 |
|
583.65 |
Q |
0.5 |
15, 20 |
0.072 |
|
583.65 |
Q |
1 |
15, 20 |
0.072 |
|
583.65 |
Q |
2 |
15, 20 |
0.290 |
|
583.65 |
Q |
5 |
15, 20 |
0.360 |
|
583.65 |
Q |
10 |
15, 20 |
0.720 |
|
583.65 |
Q |
20 |
15, 20 |
1.400 |
|
583.65 |
Q |
40 |
15, 20 |
2.900 |
|
583.65 |
Q |
50 |
15, 20 |
3.600 |
|
583.65 |
Q |
100 |
15, 20 |
7.200 |
|
583.65.65 |
Q |
1 |
15, 20 |
0.076 |
|
583.65.65 |
Q |
2 |
15, 20 |
0.160 |
|
583.65.65 |
Q |
5 |
15, 20 |
0.210 |
|
583.65.65 |
Q |
10 |
15, 20 |
0.420 |
|
584.4 |
Q |
0.01 |
8.5, 15, 20 |
0.036 |
|
584.4 |
Q |
0.05 |
8.5, 15, 20 |
0.039 |
|
584.4 |
Q |
0.1 |
8.5, 15, 20 |
0.041 |
|
584.4 |
Q |
0.2 |
8.5, 15, 20 |
0.047 |
|
584.4 |
Q |
0.5 |
8.5, 15, 20 |
0.095 |
|
584.4 |
Q |
1 |
8.5, 15, 20 |
0.12 |
|
584.4 |
Q |
2 |
8.5, 15, 20 |
0.24 |